C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/10 (2006.01) A61P 35/00 (2006.01) C07K 16/00 (2006.01) C07K 16/16 (2006.01) C07K 16/28 (2006.01) C12N 15/09 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2631184
The present invention provides monovalent antibodies with a long half-life when administered in vivo, methods of making such monovalent antibodies, pharmaceutical compositions comprising such antibodies, and uses of the monovalent antibodies.
La présente invention concerne des anticorps monovalents présentant une longue demi-vie lors d'une administration in vivo, des procédés de fabrication de ces anticorps monovalents, des compositions pharmaceutiques renfermant lesdits anticorps, ainsi que l'utilisation de ces anticorps monovalents.
Beurskens Frank
Bleeker Willem Karel
Parren Paul
Schuurman Janine
Van Berkel Patrick
Borden Ladner Gervais Llp
Genmab A/s
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