Recombinant mva virus, and the use thereof

Details Recombinant mva virus, and the use thereof Recombinant mva virus, and the use thereof

C - Chemistry, Metallurgy

12

N

C12N 7/01 (2006.01) A61K 39/00 (2006.01) A61P 37/04 (2006.01) C07K 14/16 (2006.01) C12N 5/10 (2006.01) C12N 9/02 (2006.01) C12N 9/12 (2006.01) C12N 15/86 (2006.01) C12N 15/863 (2006.01) C12P 19/34 (2006.01) C12P 21/02 (2006.01) A61K 39/285 (2006.01)

Patent

CA 2225278

Recombinant MVA viruses containing and capable of expressing foreign genes which is inserted at the site of a naturally occurring deletion within the MVA genome, and the use of such recombinant MVA viruses for the production of polypeptides, e.g. antigenes or therapeutic agents, and for the production of recombinant viruses for vaccines, or viral vectors for gene therapy.

Cette invention concerne des virus MVA recombinants contenant des gènes étrangers et capables de les exprimer, gènes qui sont insérés sur le site d'une délétion naturelle du génome MVA, et l'utilisation de ces virus MVA recombinants pour la production de polypeptides, tels que des antigènes ou des agents thérapeutiques, ainsi que pour la production de virus recombinants destinés à des vaccins ou de vecteurs viraux destinés à la thérapie génique.

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