Recombinant mva virus, and the use thereof

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 7/01 (2006.01) A61K 39/21 (2006.01) A61P 31/18 (2006.01) C07K 14/16 (2006.01) C12N 7/02 (2006.01) C12N 15/863 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2596274

Recombinant MVA viruses containing and capable of expressing foreign genes which is inserted at the site of a naturally occurring deletion within the MVA genome, and the use of such recombinant MVA viruses for the production of polypeptides, e.g. antigenes or therapeutic agents, and for the production of recombinant viruses for vaccines, or viral vectors for gene therapy.

Virus MVA recombinants contenant des gènes étrangers insérés à l'endroit d'une délétion naturelle dans le génome de MVA et capables d'exprimer ces gènes, et utilisation de ces virus pour produire des polypeptides, par exemple des antigènes ou des agents thérapeutiques, et pour produire des virus recombinants destinés à des vaccins ou à des vecteurs viraux en vue d'une thérapie génique.

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