Recombinant mycobacterium strain expressing a mycobacterial...

Details Recombinant mycobacterium strain expressing a mycobacterial... Recombinant mycobacterium strain expressing a mycobacterial...

C - Chemistry, Metallurgy

12

N

C12N 15/63 (2006.01) A61K 35/74 (2006.01) A61K 39/04 (2006.01) C07K 14/35 (2006.01)

Patent

CA 2658713

The invention relates to a recombinant vector comprising a mycobacterial FAP protein coding sequence under the transcriptional control of a promoter active under hypoxia conditions and its use for the prevention and the treatment of epithelial tumors.

L'invention concerne un vecteur recombinant contenant une séquence de codage d'une protéine FAP de mycobactérie soumise au contrôle, pour la transcription, d'un promoteur actif en situation d'hypoxie et son utilisation dans la prévention et le traitement de tumeurs épithéliales.

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