Recombinant n-glycosylated proteins from procaryotic cells

C - Chemistry – Metallurgy – 12 – P

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C12P 21/00 (2006.01) C12N 9/10 (2006.01) C12N 15/70 (2006.01)

Patent

CA 2607595

The present invention relates to recombinant N-glycosylated proteins, comprising one or more introduced N-glycosylated optimized amino acid sequence(s), nucleic acids encoding these proteins as well as corresponding vectors and host cells. In addition, the present invention is directed to the use of said proteins, nucleic acids, vectors and host cells for preparing medicaments. Furthermore, the present invention provides methods for producing said proteins.

Protéines N-glycosylées de recombinaison, comprenant une ou plusieurs séquences d'acides aminés N-glycosylées optimisées introduites, des acides nucléiques codant ces protéines et des vecteurs et cellules hôtes correspondants, et par ailleurs utilisation des protéines, acides nucléiques, vecteurs et cellules hôtes en question pour l'élaboration de médicaments, et enfin procédés d'utilisation des protéines considérées.

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