Recombinant oleandolide polyketide synthase

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 15/54 (2006.01) C12N 1/21 (2006.01) C12N 15/52 (2006.01) C12N 15/62 (2006.01) C12N 15/63 (2006.01) C12N 15/74 (2006.01) C12P 19/62 (2006.01)

Patent

CA 2347412

Recombinant DNA compounds that encode all or a portion of the oleandolide polyketide synthase are used to express recombinant polyketide synthase genes in host cells for the production of oleandolide, oleandolide derivatives, and polyketides that are useful as antibiotics and motilides.

Cette invention se rapporte à des composés d'ADN recombinés qui codent la totalité ou une partie de l'oléandolide-polykétide-synthase et qui sont utilisés pour exprimer des gènes de polykétide-synthase recombinée dans des cellules hôtes pour la production d'oléandolide, de dérivés d'oléandolide et de polykétides utiles comme antibiotiques et motilides.

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