Recombinant or transgenic factor vii composition, each...

A - Human Necessities – 61 – K

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A61K 38/48 (2006.01) C12N 9/64 (2006.01)

Patent

CA 2652496

The invention concerns a recombinant or transgenic factor VII composition, each factor VII molecule of the composition having two N-glycosylation sites, wherein among all the FVII molecules of the composition the proportion of glycan units Gal.alpha.1,3Gal ranges between 0 and 40%. The invention also concerns a method for preparing such a FVII composition.

L'invention concerne une composition de facteur VII recombinant ou transgénique, chaque molécule de facteur VII de la composition présentant deux sites de N-glycosylation, dans laquelle parmi toutes les molécules de FVII de la composition, le taux de motifs glycanniques Gal.alpha.l,3Gal est compris entre 0 et 4%. L'invention concerne également un procédé pour préparer une telle composition de FVII

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