A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/36 (2006.01) A61K 38/48 (2006.01) C07K 14/745 (2006.01) C12P 21/00 (2006.01)
Patent
CA 2658800
The present invention concerns a recombinant or transgenic factor VII composition, each factor VII molecule of the composition having glycan forms linked to N-glycosylation sites, wherein among all the factor VII molecules in said composition, glycan, biantennary, bisialylated, and non-fucosylated forms are in the majority. The invention also concerns such a composition for use as a medication, and a method for preparing said composition, among others.
La présente invention concerne une composition de facteur VII recombinant ou transgénique, chaque molécule de facteur VII de la composition comportant des formes glycanniques liées aux sites de N-glycosylation, dans laquelle parmi toutes les molécules de facteur VII de ladite composition, des formes glycanniques biantennées, bisialylées et non fucosylées sont majoritaires. L'invention concerne également une telle composition pour son utilisation comme médicament, et, également, un procédé permettant de préparer entre autres ladite composition.
Bihoreau Nicolas
Chtourou Abdessatar Sami
Nony Emmanuel
Gowling Lafleur Henderson Llp
Lfb Biotechnologies
LandOfFree
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