C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
195/1.18, 195/1.
C12N 15/00 (2006.01) C07K 14/02 (2006.01) C12N 15/62 (2006.01) C12N 15/80 (2006.01) C12N 15/81 (2006.01) C12P 21/02 (2006.01)
Patent
CA 1270217
Abstract: The invention concerns a recombinant plasmid provided with Hepatitis B virus gene, which comprises a plasmid vector containing a yeast gene and an E. coli gene and carrying the expression control region of the repressible acid phosphatase gene of yeast and a Hepatitis B virus gene recombined therewith under control of the phosphatase promoter. The invention also provides a transformed yeast which is prepared by transforming a yeast with the recombinant plasmid, and a method of producing Hepatitis B virus surface antigen on a large scale by culturing the transformed yeast in a medium. The Hepatitis B virus surface antigen prepared by the present invention has the same immunological properties as those of the natural antigen from human blood plasma and is useful for the preparation of Hepatitis B virus vaccine and diagnostic reagents.
434726
Hamada Fukusaburo
Matsubara Kenichi
Miyanohara Atsushi
Nozaki Chikateru
Ohtomo Nobuya
Director Of Finance Division Science And Technology Agency Minister's Secretariat
Kirby Eades Gale Baker
LandOfFree
Recombinant plasmid provided with hepatitis b virus gene,... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Recombinant plasmid provided with hepatitis b virus gene,..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recombinant plasmid provided with hepatitis b virus gene,... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1216190