C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) C07K 14/52 (2006.01) C07K 14/525 (2006.01) C07K 14/705 (2006.01) C07K 14/715 (2006.01) C07K 19/00 (2006.01) C12N 15/12 (2006.01) C12N 15/19 (2006.01) C12N 15/28 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01)
Patent
CA 2470564
The present invention relates, in part, to a polypeptide domain having reduced immunogenicity that is capable of inducing trimers in heterologous polypeptides, fusion polypeptides comprising the trimer inducing domain, nucleic acids encoding the polypeptides of the invention and methods of making and using the same.
L'invention concerne, en partie, un domaine polypeptidique à immunogénécité réduite capable d'induire des trimères dans des polypeptides hétérologues, des polypeptides de fusion comprenant le domaine induisant les trimères, des acides nucléiques codant pour les polypeptides de l'invention et des procédés de production et d'utilisation de ces polypeptides.
Gowling Lafleur Henderson Llp
Immunex Corporation
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