C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/86 (2006.01) A61K 31/70 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C12N 7/01 (2006.01) C12N 15/863 (2006.01)
Patent
CA 2250058
A recombinant pox virus encoding a myelin protein is described. The recombinant pox virus can be used for generating an immune response to the myelin protein. This method involves introducing a sufficient amount of the pox virus to present the myelin protein to the immune system, expressing this myelin protein and presenting the myelin protein to the immune system.
L'invention concerne un poxvirus recombinant codant pour une protéine de la myéline, qui peut être utilisé pour provoquer des réponses immunitaires contre ladite protéine. La méthode comprend l'introduction d'une quantité suffisante de poxvirus pour présenter la protéine de myéline au système immunitaire, l'expression de ladite protéine et sa présentation au système immunitaire.
Genain Claude P.
Gritz Linda
Hauser Stephen L.
Letvin Norman
Panicali Dennis
Beth Israel Deaconess Medical Center Inc.
Swabey Ogilvy Renault
The Regents Of The University Of California
Therion Biologics Corporation
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