Recombinant poxvirus-feline infectious peritonitis virus,...

C - Chemistry – Metallurgy – 12 – N

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C12N 7/01 (2006.01) A61K 39/215 (2006.01) A61K 39/275 (2006.01) A61K 39/295 (2006.01) C07K 14/165 (2006.01) C12N 7/00 (2006.01) C12N 7/04 (2006.01) C12N 15/86 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2237807

Attenuated recombinant viruses containing DNA encoding FIPV antigen(s), compositions thereof, as well as methods for making and using the compositions, expression products therefrom, and antibodies generated, are disclosed and claimed. The recombinant viruses can be NYVAC or ALVAC recombinant viruses. The compositions and products therefrom and antibodies generated have several preventive, therapeutic and diagnostic uses.

L'invention porte sur des virus de recombinaison atténués dont l'ADN code pour des antigènes de type FIPV (péritonite infectieuse du chat), sur des compositions les contenant, sur des procédés d'obtention et d'utilisation de ces compositions, sur leurs produits d'expression, et sur les anticorps produits. Ce virus de recombinaison peut être du type NYVAC ou ALVAC, et les compositions et produits qui en dérivent, ainsi que les anticorps générés ont de nombreuses applications dans les domaines de la prévention, de la thérapie et du diagnostic.

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