A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/295 (2006.01) A61K 39/12 (2006.01) A61K 39/205 (2006.01) A61K 39/275 (2006.01) C07K 14/145 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2223416
Attenuated recombinant viruses containing DNA encoding a rabies virus antigen in a "cocktail" or combination or multivalent compositions as well as methods for making and using the compositions, expression products therefrom, and antibodies generated, are disclosed and claimed. The recombinant viruses can be NYVAC or ALVAC recombinant viruses. The compositions and products therefrom and antibodies generated have several preventive, therapeutic and diagnostic uses.
L'invention concerne des virus recombinants affaiblis qui contiennent l'ADN codant l'antigène du virus de la rage dans un "cocktail" ou combinaison de compositions polyvalentes, ainsi que des procédés de préparation et d'utilisation de ces compositions, leurs produits d'expression et les anticorps ainsi générés. Les virus recombinants peuvent être des virus recombinants de type NYVAC ou ALVAC. Les compositions, ainsi que les produits dérivés de celles-ci et les anticorps qu'elles génèrent, ont différentes applications prophylactiques, thérapeutiques et diagnostiques.
Maki Joanne
Paoletti Enzo
Smart & Biggar
Virogenetics Corporation
LandOfFree
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