Recombinant production of heparin binding proteins

Details Recombinant production of heparin binding proteins Recombinant production of heparin binding proteins

C - Chemistry, Metallurgy

07

K

C07K 14/52 (2006.01)

Patent

CA 2633554

A process for recovering and purifying refolded heparin binding proteins produced in heterologous host cells includes the step of incubation of the solubilized protein with a polyanionic species such as dextran sulfate.

Le procédé faisant l'objet de cette invention, destiné à recueillir et à purifier des protéines de liaison d'héparine repliées, produites dans des cellules hôtes hétérologues, inclut l'étape consistant à incuber la protéine solubilisée avec une espèce polyanionique telle que du sulfate de dextrane.

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