C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 31/7088 (2006.01) A61K 39/09 (2006.01) A61K 39/40 (2006.01) A61K 48/00 (2006.01) C07K 14/315 (2006.01) C07K 16/12 (2006.01) C07K 19/00 (2006.01) C12N 15/63 (2006.01) C12P 21/00 (2006.01) G01N 33/569 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2432426
The present invention discloses amino acid sequences and nucleic acid sequences relating to a Streptococcus Pneumoniae surface associated Pneumo Protective Protein (PPP) having a molecular weight of about 20 kilo Daltons (kDa). The PPP exhibits the ability to reduce colonization of pneumococcal bacteria. Thus the present invention also pertains to compositions for the treatment and prophylaxis of infection or inflammation associated with bacterial infection.
L'invention concerne des séquences d'acides aminés et d'acides nucléiques correspondant à la protéine pneumoprotectrice (PPP) associée à la surface de Streptococcus Pneumoniae et présentant un poids moléculaire d'environ 20 kDa. Cette PPP est capable de réduire la formation de colonies bactériennes pneumococciques. Par ailleurs, l'invention concerne des compositions utilisées pour traiter et prévenir les infections ou les inflammations associées à une infection bactérienne.
Green Bruce A.
Masi Amy W.
Robic
Wyeth
LandOfFree
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