C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) A61K 38/47 (2006.01) C12N 9/10 (2006.01) C12N 9/24 (2006.01) C12N 9/96 (2006.01) C12N 15/54 (2006.01) C12N 15/56 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2226258
A recombinant protein having bacteriophage endosialidase enzymatic activity obtainable by expression from a recombinant vector comprising a DNA sequence encoding a bacteriophage endosialidase linked to a DNA sequence of an expression vector which expresses a polypeptide which adds to the N-terminus of the endosialidase, or an analogue of said protein, which is a mutant, functional fragment or derivative of said protein having endosialidase enzymatic activity.
Cette protéine recombinée présente une activité enzymatique endosialidase de bactériophage que l'on peut obtenir par expression à partir d'un vecteur recombiné comprenant une séquence d'ADN codant une endosialidase de bactériophage liée à une séquence d'ADN d'un vecteur d'expression, lequel exprime un polypeptide qui s'ajoute à la terminaison N de l'endosialidase, ou bien un analogue de ladite protéine constituant un mutant, un fragment fonctionnel ou un dérivé de ladite protéine présentant une activité enzymatique endosialidase.
Bryant Jonathan Mark
Luzio John Paul
Taylor Peter William
Cambridge University Technical Services Limited
Endozyme Limited
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