C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/18 (2006.01) C07K 14/475 (2006.01) C07K 19/00 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2319211
Recombinant proteins deriving from recombination of structural domains deriving from the a subunits of HGF and/or MSP growth factors. The recombinant proteins of the present invention have biological activity, and protect cells from death (apoptosis) induced by chemotherapeutic drugs. These molecules can conveniently be used to prevent or to treat the toxic side effects of chemotherapeutic agents used in cancer therapy.
L'invention concerne des protéines recombinées, obtenues par recombinaison de domaines structuraux dérivés des sous-unités .alpha. du facteur de croissance des hépatocytes (HGF) et/ou de la protéine de stimulation des macrophages (MSP). Les protéines recombinées de l'invention possèdent une activité biologique et protègent les cellules de la mort (apoptose), laquelle est induite par des médicaments chimiothérapiques. On peut utiliser ces molécules de manière pratique pour empêcher ou prévenir les effets secondaires toxiques des agents chimiothérapiques utilisés en thérapie anticancéreuse.
Caselli Gianfranco
Collesi Chiara
Comoglio Paolo
Medico Enzo
Michieli Paolo
Dompe Pha.r.ma S.p.a.
Dompe S.p.a.
Kirby Eades Gale Baker
LandOfFree
Recombinant proteins derived from hgf and msp does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Recombinant proteins derived from hgf and msp, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recombinant proteins derived from hgf and msp will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2055990