C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/18 (2006.01) C07K 14/475 (2006.01) C07K 19/00 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2319144
Recombinant proteins deriving from recombination of structural domains deriving from alpha and beta subunits of HGF and/or MSP growth factors. The recombinant proteins of the present invention contain domains selected from HGF and MSP to protect cells from death (apoptosis) induced by chemotherapeutics.
L'invention concerne des protéines recombinées provenant des domaines structurels issus des sous-unités alpha et bêta du facteur de croissance des hépatocytes (HGF) et du facteur stimulant les macrophages (MSP). Les protéines recombinées de la présente invention contiennent des domaines sélectionnés à partir du HGF et du MSP pour protéger les cellules contre la mort (apoptose) induite par la chimiothérapie.
Caselli Gianfranco
Collesi Chiara
Comoglio Paolo
Medico Enzo
Michieli Paolo
Dompe Pha.r.ma S.p.a.
Dompe S.p.a.
Kirby Eades Gale Baker
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