Recombinant ricin toxin

Details Recombinant ricin toxin Recombinant ricin toxin

C - Chemistry, Metallurgy

12

N

530/13, 195/39.1

C12N 15/70 (2006.01) C07K 14/415 (2006.01) C12N 1/21 (2006.01) C12N 9/00 (2006.01) C12N 15/29 (2006.01) C12N 15/52 (2006.01)

Patent

CA 1324095

Abstract of the Disclosure DNA sequences encoding full length precursor proteins, which proteins contain both A and B portions of two ricin isotoxins and ricin agglutinin, as well as the linker regions have been determined. These DNAs or portions or modifications thereof are expressed in recombinant hosts to obtain the desired proteins or proteins which can readily be converted thereto. One of the ricin isotoxins may be related to ricin E.

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