Recombinant sendai virus

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 7/01 (2006.01) C07K 14/115 (2006.01) C12N 15/45 (2006.01) C12N 15/86 (2006.01) C12P 21/00 (2006.01)

Patent

CA 2236378

A method for reconstituting Sendai virions which comprises introducing the genome of Sendai virus into a host wherein all of the early replication genes have been expressed. This method enables gene manipulations of Sendai virus and thus makes it possible to utilize Sendai virus efficiently as a vector.

Cette invention concerne un procédé permettant de reconstituer des virions sendai, lequel procédé consiste à introduire le génome d'un virus sendai dans un hôte dans lequel les gènes de réplication précoces ont tous été exprimés. Ce procédé permet d'effectuer des manipulations géniques du virus sendai, et d'utiliser ainsi efficacement ce dernier en qualité de vecteur.

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