Recombinant subunit west nile virus vaccine for protection...

A - Human Necessities – 61 – K

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A61K 39/12 (2006.01) A61P 31/14 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2761262

A West Nile virus vaccine for human use is described that preferably contains a recombinantly produced form of truncated West Nile virus envelope glycoprotein and aluminum adjuvant. The vaccine is acceptable for use in the general population, including immunosuppressed, immunocompromised, and immunosenescent individuals. The vaccine is safe and effective for use in all healthy and at-risk populations. A pharmaceutically acceptable vehicle may also be included in the vaccine.

La présente invention concerne un vaccin contre le virus du Nil occidental pour usage humain, qui contient de préférence une forme produite de manière recombinante de glycoprotéine d'enveloppe de virus du Nil occidental tronquée et un adjuvant aluminium. Ledit vaccin est acceptable pour être utilisé auprès de l'ensemble de la population, y compris auprès d'individus immunodéprimés, immunodéficients et immunosénescents. Ledit vaccin peut être utilisé avec fiabilité et efficacité sur toutes les populations saines ou à risque. Un vecteur pharmaceutiquement acceptable peut également être compris dans le vaccin.

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