Recombinant terminal deoxynucleotidyl transferase with...

C - Chemistry – Metallurgy – 12 – N

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C12N 9/12 (2006.01) C12N 9/10 (2006.01) C12N 15/54 (2006.01) C12N 15/63 (2006.01) C12P 19/34 (2006.01) C12P 21/02 (2006.01) C12Q 1/48 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2423887

Truncated terminal deoxynucleotidyl transferase (TdT) derivative from calf thymus characterized in that the derivative in comparison to the native TdT is N- terminally truncated by up to 161 amino acids and has a 20- 30-fold higher enzyme activity in solutions containing Co~ions, and it's recombinant production and use.

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