Recombinant timothy grass pollen allergen ph1 pii

Details Recombinant timothy grass pollen allergen ph1 pii Recombinant timothy grass pollen allergen ph1 pii

C - Chemistry, Metallurgy

12

N

C12N 15/29 (2006.01) A61K 39/36 (2006.01) C07K 4/10 (2006.01) C07K 14/415 (2006.01) C12N 9/38 (2006.01) G01N 33/564 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2136973

(54) Title: RECOMBINANT TIMOTHY GRASS POLLEN ALLERGEN Phi p II (57) Abstract: A recombinant DNA molecule codes for a peptide with the antigenicity of timothy grass pollen allergens Phi p II. The amino acid sequence (5) and the most important B coil and T cell epitopes of the molecule are derived therefrom. The recombinant Phi p II allergies is expressed in Escherichia coli and binds serum IgE of more than 60 % of all those allergic to grass pollen and many therefore be used in the same way as the naturally occurring Phi p II for processes based on antigen- antibody interaction, mediator release and T cell reactivity. Phi p II Image

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