Recombinant tissue protective cytokines and encoding nucleic...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/18 (2006.01) A61K 38/18 (2006.01) C07K 14/505 (2006.01) C12N 15/87 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2491567

Methods and compositions are provided for protecting or enhancing a responsive cell, tissue, organ or body part function or viability in vivo, in situ or ex vivo in mammals, including human beings, by systemic or local administration of an erythropoietin receptor activity modulator, such as an recombinant tissue protective cytokine.

L'invention concerne des méthodes et des compositions destinées à protéger ou améliorer la fonction ou la viabilité d'une cellule, d'un tissu, d'un organe ou d'une partie du corps sensible dans des conditions in vivo, in situ ou ex vivo chez des mammifères, y compris des êtres humains, par administration systémique ou locale d'un modulateur de l'activité des récepteurs de l'érythropoïétine, tel qu'une cytokine protectrice des tissus recombinée.

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