C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 38/16 (2006.01) A61K 39/08 (2006.01) C07K 14/33 (2006.01) C12N 1/21 (2006.01) C12N 15/62 (2006.01) G02B 26/00 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2365915
The present invention relates to the field of medical immunology and further to pharmaceutical compositions, methods of making and methods of use of vaccines. More specifically this invention relates to recombinant proteins derived from the genes encoding Clostridium difficile toxin A and toxin B, and their use in an active vaccine against C. difficile.
L'invention concerne le domaine de l'immunologie médicale. L'invention concerne également des compositions pharmaceutiques, des techniques de fabrication et d'utilisation de vaccins. Plus particulièrement, l'invention concerne des protéines recombinées dérivées des gènes codant pour la toxine A et la toxine B du Clostridium difficile et leur utilisation dans un vaccin actif contre le C. difficile.
Lyerly David M.
Moncrief J. Scott
Phelps Carol
Wilkins Tracy D.
Zheng Limin
Fetherstonhaugh & Co.
Intercell Usa Inc.
Techlab Inc.
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