C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/40 (2006.01) C07K 14/79 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2103583
Recombinant transferrin, transferrin half-molecules and mutant transferrins hav-ing altered metal-binding or other properties are described. The recombinant transferrin molecules are expressed in functionnal form by stable eukaryotic cell lines such as baby hamster kidney cells transformed with an ex-pression vector encoding the recombinant molecule. The recombinant transferrins can be used in metal chelation therapy to bind and clear excess toxic metals in patients suf-fering from metal overloads.
Funk Walter D.
Macgillivray Ross T.a.
Mason Anne B.
Woodworth Robert C.
Borden Ladner Gervais Llp
The University Of British Columbia
University Of Vermont And State Agricultural College (the)
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