Recombinant vaccine against lyme disease

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/20 (2006.01) A61K 39/02 (2006.01) A61K 39/40 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2123121

2123121 9310237 PCTABS00022 A highly-antigenic, recombinant polypeptide of a molecular weight of about 110-kD by SDS-PAGE is disclosed, which is derived by transforming E. coli with a 7.1 kB DNA fragment from EcoR1-digested B. burgdorferi DNA, followed by identification of cloned transformants expressing polypeptides which bind to anti-B. burgdorferi antibodies.

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