Recombinant vaccines and use thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/62 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2542269

The present invention relates to fusion molecules of antigens, the nucleic acids coding therefor and the use of such fusion molecules and nucleic acids. In particular, said invention relates to fusion molecules, comprising an antigen and the transmembrane region and cytoplasmic region of a MHC molecule and/or the cytoplasmic region of a MHC or a SNARE molecule.

La présente invention concerne des molécules de fusion d'antigènes, les acides nucléiques qui codent pour celles-ci, et l'utilisation de molécules de fusion et d'acides nucléiques de ce type. L'invention concerne en particulier des molécules de fusion qui comprennent un antigène ainsi que la zone transmembranaire et la zone cytoplasmique d'une molécule CMH ou la zone cytoplasmique d'une molécule de CMH ou d'une molécule SNARE.

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