C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/86 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C12N 5/10 (2006.01) C12N 7/01 (2006.01) C12N 7/04 (2006.01) C12N 15/864 (2006.01)
Patent
CA 2221292
The present invention relates to a system for replication and encapsidation of recombinant DNA fragments into virus particles comprised of adeno-associated viral (AAV) capsid proteins; said system uses a 165 basepair fragment of DNA which contains AAV inverted terminal repeat sequences and which is used to engineer expression vectors useful for gene therapy. The invention provides a means of obtaining recombinant viral stocks that may be used to treat patients suffering from genetic diseases.
L'invention concerne un système de réplication et d'encapsidation de fragments d'ADN de recombinaison pour former des particules virales constituées de capsides de virus ayant les caractéristiques d'un adénovirus; dans ledit système on utilise un fragment à 165 paires de bases d'ADN contenant des séquences de répétitions terminales inverses dudit virus associé à l'adénovirus pour la manipulation des vecteurs d'expression utiles pour la thérapie génique. L'invention se rapporte aussi à un moyen permettant de produire des populations virales de recombinaison pouvant être utilisées pour traiter des patients souffrant de maladies génétiques.
Samulski Richard J.
Xiao Xiao
Osler Hoskin & Harcourt Llp
University Of Pittsburgh
LandOfFree
Recombinant viral vector system does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Recombinant viral vector system, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recombinant viral vector system will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1736760