Recombinant virus production using mammalian cells in...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 7/01 (2006.01) A61K 48/00 (2006.01) C12N 7/00 (2006.01) C12N 15/864 (2006.01)

Patent

CA 2713338

The invention generally provides methods for producing recombinant AAV viral particles using cells grown in suspension. The invention provides recombinant AAV particles for use in methods for delivering genes encoding therapeutic proteins, and methods for using the recombinant AAV particles in gene therapy.

L'invention concerne généralement des procédés de production de particules virales de VAA recombinant en utilisant des cellules cultivées en suspension. L'invention concerne des particules de VAA recombinant destinées à être utilisées dans des procédés de distribution de protéines thérapeutiques codant des gènes, ainsi que des procédés d'utilisation des particules de VAA recombinant dans une thérapie génique.

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