Recombinant viruses expressing lecithin-cholesterol...

Details Recombinant viruses expressing lecithin-cholesterol... Recombinant viruses expressing lecithin-cholesterol...

C - Chemistry, Metallurgy

12

N

C12N 7/01 (2006.01) A61K 48/00 (2006.01) C12N 7/04 (2006.01) C12N 9/10 (2006.01) C12N 15/86 (2006.01) C12N 15/861 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2214010

Defective recombinant viruses containing an inserted gene coding for all or part of lecithin-cholesterol acyltransferase (LCAT) or a variant thereof, pharmaceutical compositions containing said viruses, and the use thereof for treating or preventing dyslipoproteinaemia-related diseases, are disclosed.

La présente invention concerne des virus recombinants défectifs contenant un gène inséré codant pour tout ou partie de la lécithine cholestérol acyltransférase (LCAT) ou d'un variant de celle-ci, les compositions pharmaceutiques comprenant ces virus, et leur utilisation pour le traitement ou la prévention des pathologies liées aux dyslipoprotéinémies.

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