Recombining viral vectors for the tetracycline-regulated...

Details Recombining viral vectors for the tetracycline-regulated... Recombining viral vectors for the tetracycline-regulated...

C - Chemistry, Metallurgy

12

N

C12N 15/861 (2006.01) A61K 48/00 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2481244

The invention relates to recombining viral vectors which can be suppressed in a highly efficient manner by means of tetracycline or tetracycline derivatives, and the use thereof for expressing genes in eukaryotic cells, particularly within the framework of gene therapy.

L'invention concerne des vecteurs viraux recombinants qui peuvent être supprimer de manière très efficace par la tétracycline ou par des dérivés de la tétracycline comme, par exemple, la doxycycline. La présente invention porte également sur l'utilisation de ces vecteurs viraux pour réaliser une expression génique dans des cellules eucaryotes, notamment dans le cadre de la thérapie génique.

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