Reconstituted surfactants having improved properties

Details Reconstituted surfactants having improved properties Reconstituted surfactants having improved properties

C - Chemistry, Metallurgy

07

K

C07K 14/785 (2006.01) A61K 38/16 (2006.01) A61P 11/00 (2006.01)

Patent

CA 2666344

The present invention is directed to a reconstituted surfactant comprising a lipid carrier, a polypeptide analogue of the native surfactant protein SP-C, and a polypeptide analogue of the native surfactant protein SP-B. The invention is also directed to the pharmaceutical compositions thereof and to its use for the treatment or prophylaxis of RDS and other respiratory disorders.

La présente invention porte sur un agent tensioactif reconstitué comportant un support lipidique, un analogue polypeptidique de la protéine d'agent tensioactif native SP-C, et un analogue polypeptidique de la protéine d'agent tensioactif native SP-B. L'invention porte également sur les compositions pharmaceutiques dudit agent et sur leur utilisation pour le traitement ou la prophylaxie de RDS et d'autres maladies respiratoires.

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