Recovery of urokinase compounds

Details Recovery of urokinase compounds Recovery of urokinase compounds

C - Chemistry, Metallurgy

12

N

195/78, 195/39.1

C12N 9/72 (2006.01)

Patent

CA 1309961

ABSTRACT OF THE DISCLOSURE Disclosed is a method of recovering urokinase compounds from media and cell extracts. The method comprises contacting the urokinase compound-containing solution with a silicaceous matrix material comprising covalently hound polymer having plural anionic groups. Selective elution of the urokinase compound can produce eluants of high specific activity. The method can succeed in recovering greater than 90% of the urokinase activity from the crude solution.

602566

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