Recovery of viruses

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 7/02 (2006.01)

Patent

CA 2475165

A method for recovering a desired virus type from a sample containing mixture of unwanted components by electrophoresis, the method comprising placing the sample in a first sample chamber of an electrophoresis apparatus comprising an ion-permeable separation barrier disposed between the first sample chamber and a second sample chamber; applying an electric potential across the first and second sample chambers whereby either the desired virus type moves through the separation barrier or the unwanted components move through the separation barrier and at least a portion of the desired virus type is located on one side of the separation barrier while unwanted components are located on the other side of the separation barrier; and maintaining step (b) until the desired amount of the desired virus type is located on one side of the separation barrier.

L'invention concerne un procédé de récupération d'un virus recherché, par électrophorèse à partir d'un échantillon contenant un mélange de composants indésirables, le procédé consistant à placer l'échantillon dans une première chambre d'un appareil d'électrophorèse comprenant une barrière de séparation perméable aux ions disposée entre la première chambre d'échantillon et la seconde chambre d'échantillon, à appliquer un potentiel électrique à travers les première et seconde chambres d'échantillon grâce à quoi le virus recherché, ou les composants indésirables sont déplacés à travers la barrière de séparation et au moins une portion du type de virus recherché est placée sur un côté de la barrière de séparation alors que les composants indésirables sont placés de l'autre côté de cette barrière, et à continuer l'étape (b) jusqu'à ce que la quantité souhaitée du virus recherché soit placée sur un des côtés de la barrière de séparation.

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