C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 50/28 (2006.01) A61K 31/122 (2006.01) A61K 31/355 (2006.01) C07D 311/72 (2006.01)
Patent
CA 2610152
Methods of treating or suppressing mitochondrial diseases, such as Friedreich's ataxia (FRDA), Leber's Hereditary Optic Neuropathy (LHON), mitochondrial myopathy, encephalopathy, lactacidosis, stroke (MELAS), or Kearns-Sayre Syndrome (KSS) are disclosed, as well as compounds useful in the methods of the invention, such as alpha- tocopherol quinone. Methods and compounds useful in treating other disorders are also disclosed. Energy biomarkers useful in assessing the metabolic state of a subject and the efficacy of treatment are also disclosed. Methods of modulating, normalizing, or enhancing energy biomarkers, as well as compounds useful for such methods, are also disclosed.
L'invention concerne des procédés pour traiter ou éliminer des maladies mitochondriales telles que l'ataxie de Friedreich (FRDA), la neuropathie optique héréditaire de Leber (LHON), la myopathie mitochondriale, l'encéphalopathie, la lactacidose, l'ACV (MELAS), ou le syndrome de Kearns-Sayre (KSS), ainsi que des composés utiles dans les procédés de l'invention tels que l'alpha-tocophérol-quinone. L'invention concerne également des procédés et des composés utiles dans le traitement d'autres troubles, ainsi que des biomarqueurs d'énergie utiles pour évaluer l'état métabolique d'un sujet et l'efficacité de traitement. Elle porte également sur des procédés de modulation, de normalisation ou d'amélioration des biomarqueurs d'énergie ainsi que des composés utiles dans la mise en pratique de ces procédés.
Hecht Sidney M.
Miller Guy M.
Borden Ladner Gervais Llp
Edison Pharmaceuticals Inc.
LandOfFree
Redox-active therapeutics for treatment of mitochondrial... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Redox-active therapeutics for treatment of mitochondrial..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Redox-active therapeutics for treatment of mitochondrial... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1678723