Reduced total fluence photodynamic therapy of choroidal...

Details Reduced total fluence photodynamic therapy of choroidal... Reduced total fluence photodynamic therapy of choroidal...

A - Human Necessities

61

K

A61K 41/00 (2006.01)

Patent

CA 2437557

The invention relates to the use of reduced fluence rate PDT to treat neovasculature, particularly choroidal neovasculature (CNV). Reduced fluence rate PDT decreases the likelihood of molecular oxygen being the limiting factor in the photodynamic reaction so that the concentration of either photons (light intensity) or photosensitizer in the target tissue controls the photodynamic reaction.

L'invention concerne l'utilisation de la thérapie photodynamique à débit de fluence réduit (PDT) afin de traiter la néovascularisation, notamment la néovascularisation choroïdienne (NCR). La thérapie photodynamique à débit de fluence réduit (PDT) diminue les probabilités que l'oxygène moléculaire soit le facteur limitatif dans la réaction photodynamique de sorte que la concentration de photons (intensité lumineuse) ou de photosensibilisateur dans le tissu cible règle la réaction photodynamique.

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