Reducing arthritis and lameness in subjects by growth...

Details Reducing arthritis and lameness in subjects by growth... Reducing arthritis and lameness in subjects by growth...

C - Chemistry, Metallurgy

12

N

C12N 15/16 (2006.01) A61K 38/25 (2006.01) A61P 19/02 (2006.01) C07K 14/60 (2006.01) C12N 15/85 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2592891

One aspect of the current invention is a method of preventing and / or treating arthritis and / or preventing or treating lamenes in a subjetc. Additionally, subject quality of like and welfare, and body conditions scores are improved by utilizing methodology that administers the nucleic acid expression construct encoding a GHRH or functional biological equivalent to a subject throught a parental route of administration. Following a single dose of nucleic acid expression vector, subjects are healthier and effects demonstrated long term without additional administration(s) of the expression construct.

L'invention concerne, dans un aspect, une méthode de prévention et/ou de traitement de l'arthrite et/ou de la boiterie chez un sujet. En outre, la qualité d'appétition et de bien-être, ainsi que la note d'état corporel sont améliorées chez ledit sujet par l'utilisation d'une méthodologie consistant à administrer à un sujet, par une voie d'administration parentérale, la construction d'expression de l'acide nucléique codant SRIF ou un équivalent biologique fonctionnel. Après la prise d'une seule dose de vecteur d'expression de l'acide nucléique, le sujet recouvre une meilleure santé et la dose agit à long terme sans administration(s) supplémentaire(s) de la construction d'expression.

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