Reducing side effects of tramadol

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/519 (2006.01) A61K 31/135 (2006.01) A61K 31/485 (2006.01) A61P 15/10 (2006.01)

Patent

CA 2677691

The invention provides methods of reducing the side effects of tramadol. Accordingly, in one embodiment, the invention provides a method of reducing the incidence of newly-discovered side effects related to sexual function in human males taking a tramadol material. The method comprises administering a phosphodiesterase inhibitor to a male taking the tramadol material. The invention also provides pharmaceutical compositions. In one embodiment, the composition comprises a tramadol material and a phosphodiesterase inhibitor. The invention further provides kits. In one embodiment, the kit comprises a tramadol material and a phosphodiesterase inhibitor.

L'invention concerne des procédés de réduction des effets secondaires du tramadol. En conséquence, dans un mode de réalisation, l'invention concerne un procédé de réduction de l'incidence des effets secondaires nouvellement découverts liés à la fonction sexuelle chez des hommes prenant une substance à base de tramadol. Le procédé comprend l'administration d'un inhibiteur de phosphodiestérase à un homme prenant la substance à base de tramadol. L'invention concerne également des compositions pharmaceutiques. Dans un mode de réalisation, la composition comprend une substance à base de tramadol et un inhibiteur de phosphodiestérase. L'invention concerne en outre des trousses. Dans un mode de réalisation, la trousse comprend une substance à base de tramadol et un inhibiteur de phosphodiestérase.

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