Reductant composition for technetium-99m and method for...

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31/1, 167/48

G01T 1/164 (2006.01) C01G 99/00 (2010.01) A61K 51/04 (2006.01) A61K 51/08 (2006.01) A61K 51/12 (2006.01)

Patent

CA 1111765

Abstract of the Disclosure Reductant compositions for reducing technetium to produce technetium labelled ligands comprise a substrate having attached thereto a reducing complex having sufficient redox potential to reduce technetium from the +7 oxidation state. Preferably the reducing complex comprises a reducing agent for technetium and a chelating ligand therefor. Technetium labelled ligands are prepared by mixing such ligands with pertechnetate in the presence of the reductant of this invention and separating the reductant from the resulting labelled ligand. Technetium labelled ligands that are substantially free from reducing agent used in their preparation may be made in this manner.

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