Reduction giving 3-cephem compounds

Details Reduction giving 3-cephem compounds Reduction giving 3-cephem compounds

C - Chemistry, Metallurgy

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C07D 501/14 (2006.01) A61K 31/545 (2006.01) C07D 501/04 (2006.01) C07D 501/16 (2006.01) C07D 501/20 (2006.01) C07D 501/22 (2006.01) C07D 501/60 (2006.01)

Patent

CA 1069119

REDUCTION GIVING 3-CEPHEM COMPOUNDS ABSTRACT Antibacterial cephems having following formula: Image (wherein A is amino or substituted amino; COB is carboxy or pro- tected carboxy; R is two hydrogens, hydrogen and a monovalent substituent, or a divalent substituent; and n is zero or one) are prepared by reducing a compound having following formula: Image (wherein A, COB, R, and n are defined above and X is halo or sul- fonyloxy) with a reducing reagent.

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