Reduction in myocardial infarction size

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/20 (2006.01) A61K 38/17 (2006.01) A61K 38/44 (2006.01)

Patent

CA 2615887

This invention provides methods and compositions used for reducing the Myocardial Infarct (MI) size in diabetic subjects exhibiting the haptoglobin (Hp) 2 allele. Specifically, the invention relates to reduction of MI in diabetic subjects carrying the Hp-2 allele by reducing the oxidative sterss in these subjects following ischemia-reperfusion injury.

La présente invention se rapporte à des méthodes et à des compositions destinées à réduire la taille de l'infarctus du myocarde chez des sujets diabétiques présentant l'allèle de l'haptoglobine (Hp) 2. Plus précisément, l'invention concerne la réduction de l'infarctus du myocarde chez des sujets diabétiques porteurs de l'allèle Hp-2, par la réduction du stress oxydatif chez lesdits sujets à la suite d'une lésion liée d'ischémie-reperfusion.

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