A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/675 (2006.01) A61K 31/198 (2006.01) A61K 31/28 (2006.01) A61K 31/335 (2006.01) A61K 31/44 (2006.01) A61K 31/4415 (2006.01) A61K 31/444 (2006.01) A61K 31/70 (2006.01) A61K 33/32 (2006.01)
Patent
CA 2259150
The invention relates to the use of certain chelating agents and their metal chelates and to the use of certain manganese containing compounds, in particular manganese chelates, in the manufacture of a therapeutic agent for use in reducing the cardiotoxicity of an antitumor agent. Such compounds are particularly effective in reducing the side-effects of anthracycline drugs and/or paclitaxel.
L'invention concerne l'utilisation de certains agents chélatants et de leurs chélates de métaux, ainsi que de certains composés contenant du manganèse, en particulier des chélates de manganèse, dans la préparation d'un agent thérapeutique servant à diminuer la cardiotoxicité d'un agent anti-tumeurs. Ces composés sont particulièrement efficaces pour diminuer les effets secondaires de médicaments à base d'anthracycline et/ou du paclitaxel.
Jynge Per
Karlsson Jan Olof Gustav
Towart Robertson
Fetherstonhaugh & Co.
Nycomed Imaging As
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