Reduction of hair growth

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/425 (2006.01) A61K 31/135 (2006.01) A61K 31/215 (2006.01) A61K 31/275 (2006.01) A61K 31/395 (2006.01) A61K 31/505 (2006.01)

Patent

CA 2360524

Mammalian hair growth is reduced by applying to the skin an inhibitor of protein-tyrosine kinase. A method is described for applying to the skin a composition including an inhibitor of protein-tyrosine kinases in an amount effective to reduce hair growth. The unwanted hair growth which is reduced is normal hair growth. The preferred composition includes at least one inhibitor of protein-tyrosine kinase in a cosmetically and/or dermatologically acceptable vehicle. The composition may be a solid, semi- solid, or liquid. The composition may be, for example, a cosmetic and dermatologic product in the form of an, for example, ointment, lotion, foam, cream, gel, or hydroalcoholic solution. The composition may also be in the form of a shaving preparation or an aftershave.

La présente invention concerne la réduction de la pousse des poils chez les mammifères par application sur la peau d'un inhibiteur de protéine tyrosine kinase. L'invention concerne également un procédé permettant d'appliquer sur la peau une composition contenant un inhibiteur de protéines tyrosines kinases en quantité suffisante pour réduire la pousse des poils. La pousse des poils posant problème peut être une pousse normale des poils ou une pousse des poils résultant d'un état pathologique ou anormal. La composition préférée contient au moins un inhibiteur de protéine tyrosine kinase dans un excipient admis en cosmétologie et/ou en dermatologie. La composition peut se présenter sous forme solide, semi-solide ou liquide. La composition peut être notamment un produit cosmétique ou dermatologique sous forme de pommade, de lotion, de mousse, de crème, de gel ou de solution hydroalcoolique. La composition peut également se présenter sous forme de produit de rasage ou d'après rasage.

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