Reduction of low density lipoproteins in biological fluids

C - Chemistry – Metallurgy – 12 – N

Patent

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167/114, 167/103

C12N 11/10 (2006.01) A61K 35/14 (2006.01) A61K 38/46 (2006.01) A61M 1/36 (2006.01) A61M 1/16 (2006.01)

Patent

CA 1336814

A method and apparatus for reducing the levels of low density lipoproteins (LDL) in blood is disclosed. The LDL is contacted with an enzyme which modifies it in a manner such that the LDL is rapidly removed endogenously by the patients' own metabolic processes. The enzyme may be introduced into the patient by injection, transdermal transport, nasal insufflation and ingestion. Additionally, the enzyme may be contained in a reactor for both in vivo and extracorporeal use.

578283

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