Reduction of oxyradical damage in biomedical applications

Details Reduction of oxyradical damage in biomedical applications Reduction of oxyradical damage in biomedical applications

C - Chemistry, Metallurgy

07

K

C07K 7/04 (2006.01) A61K 35/14 (2006.01) A61K 38/04 (2006.01) A61K 38/38 (2006.01) C07K 14/76 (2006.01) C07K 14/765 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2035836

ABSTRACT The biliproteins delta-bilirubin and delta-bilipeptide are useful as cytoprotective antioxidants. Delta-bilipeptide as the term is used herein is a truncated form of delta-bilirubin in which an albumin analogue of 10 - 200 amino acid residues replaces the albumin portion of delta-bilirubin. Patient - administrable compositions for addition to a patient's blood to minimize oxyradical damage caused by ischemia-reperfusion injury that may result in various surgical procedures, and comprising delta-bilirubin or delta-bilipeptide, are described.

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