Reduction of scan time in imaging mass spectrometry

Details Reduction of scan time in imaging mass spectrometry Reduction of scan time in imaging mass spectrometry

G - Physics

01

N

G01N 24/00 (2006.01)

Patent

CA 2632265

Techniques are disclosed for reducing scan times in mass spectral tissue imaging studies. According to a first technique, a tissue imaging boundary is defined that closely approximates the edges of a tissue sample. According to a second technique, a low- resolution scan is performed to identify one or more areas of interest within the tissue sample, and the identified areas of interest are subsequently scanned at higher resolution.

La présente invention concerne des techniques permettant la réduction des temps de balayage dans des études d'imagerie tissulaire spectrale de masse. Selon une première technique, une limite d'imagerie tissulaire est définie qui réalise une approximation proche des bords d'un échantillon tissulaire. Selon une seconde technique, un balayage à faible résolution est effectué pour l'identification d'une ou de plusieurs zones d'intérêt dans l'échantillon tissulaire, et les zones d'intérêt identifiées sont ultérieurement balayées à une résolution supérieure.

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