Reduction of spontaneous mutation rates in cells

C - Chemistry – Metallurgy – 12 – Q

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Details

C12Q 1/02 (2006.01) C12N 1/20 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2557729

The present invention relates to processes for reducing the spontaneous mutation frequencies in cells or organisms and for producing such cells and organisms, to cells and/or organisms with reduced spontaneous mutation frequencies and to processes for the generation of expression systems for proteins, for the production of proteins and for the production of fermentation products by using cells with reduced spontaneous mutation frequencies.

La présente invention concerne des procédés destinés à la réduction des fréquences de mutation spontanée dans des cellules et des organismes et à la production de ces cellules et de ces organismes, des cellules et/ou des organismes présentant des fréquences de mutation spontanée réduites et des procédés destinés à la production de systèmes d'expression pour des protéines, à la production de protéines et à la production de produits de fermentation à l'aide de cellules présentant des fréquences de mutation spontanée réduites.

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