Reduction of the electrocardiographic qt interval for...

A - Human Necessities – 61 – K

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Details

A61K 38/28 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2422026

The present invention relates to the use of proinsulin C-peptide or a variant, derivative or fragment thereof in the manufacture of a medicament for reducing the OTc interval and the use of proinsulin C-peptide or a variant, derivative or fragment thereof in the manufacture of a medicament for reducing the risk of sudden death or 'dead in bed' syndrome; particularly in patients suffering from IDDM.

La présente invention concerne l'utilisation du peptide-C de la proinsuline ou une variante, un dérivé ou un fragment de ce dernier dans la fabrication d'un médicament permettant de réduire l'intervalle QT de l'électrocardiogramme. L'invention a aussi pour objet l'utilisation du peptide C de la proinsuline ou une variante, un dérivé ou un fragment de ce dernier dans la fabrication d'un médicament permettant de réduire le risque de mort subite ou syndrôme de mort subite du nourisson, en particulier, chez les patients souffrant de diabète insulino-dépendant.

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