Reduction of the toxic effect of impurities from raw...

C - Chemistry – Metallurgy – 12 – P

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C12P 7/64 (2006.01)

Patent

CA 2692266

There are provided bioproducts and methods of improving production of the bioproducts from engineered microbial cells, the methods comprising: providing a fermentation broth comprising a crude carbon source; inoculating said fermentation broth with said microbial cells; and incubating the inoculated fermentation broth; wherein said bioproduct is a hydrophobic solvent immiscible with said fermentation broth, and wherein a toxic side product present in said crude carbon source is soluble in said hydrophobic solvent. Also, provided are kits for practicing the methods of improving production of bioproducts.

La présente invention concerne des produits biologiques et des procédés d'amélioration de la production de produits biologiques à partir de cellules microbiennes modifiées, les procédés comprenant les étapes consistant à : fournir un bouillon de fermentation comprenant une source brute de carbone ; inoculer ledit bouillon de fermentation avec lesdites cellules microbiennes ; et incuber le bouillon de fermentation inoculé ; ledit produit biologique étant un solvant hydrophobe non miscible avec ledit bouillon de fermentation, et un produit secondaire toxique présent dans ladite source brute de carbone étant soluble dans ledit solvant hydrophobe. L'invention concerne également des kits pour réaliser les procédés d'amélioration de la production de produits biologiques.

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